NFL 2026
Week 3 · Sunday, September 27, 2026 · Levi's Stadium · 70,687 attended
Game Recap

49ers Beat Cardinals 36-30 in Week 3

San Francisco 49ers 36, Arizona Cardinals 30 at Levi's Stadium. Brock Purdy went 15 of 27 for 297 yards with 4 touchdowns.

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Quarter Scoring

Team Q1Q2Q3Q4 Total
Cardinals
06717 30
49ers
710613 36

49ers Leaders

Passing Yards
Brock Purdy
15/27, 297 YDS, 4 TD
Rushing Yards
Christian McCaffrey
15 CAR, 75 YDS, 1 TD
Receiving Yards
George Kittle
6 REC, 82 YDS, 2 TD
Tackles

Cardinals Leaders

Passing Yards
Jacoby Brissett
38/52, 280 YDS, 2 TD
Rushing Yards
Jeremiyah Love
21 CAR, 90 YDS
Receiving Yards
Michael Wilson
11 REC, 89 YDS, 1 TD
Sacks
-
Tackles

Team Stats

Cardinals Stat 49ers
27 1st Downs 23
18 Passing 1st downs 14
6 Rushing 1st downs 7
3 1st downs from penalties 2
9-18 3rd down efficiency 5-8
2-2 4th down efficiency 0-0
81 Total Plays 50
365 Total Yards 437
4.5 Yards per Play 8.7
10 Total Drives 10
272 Passing 297
38/52 Comp/Att 15/27
5.0 Yards per pass 11.0
0 Interceptions thrown 0
2-8 Sacks-Yards Lost 0-0
93 Rushing 140
27 Rushing Attempts 23
3.4 Yards per rush 6.1
3-5 Red Zone (Made-Att) 2-2
10-86 Penalties 7-69
0 Turnovers 1
0 Fumbles lost 1
0 Interceptions thrown 0
0 Defensive / Special Teams TDs 0
38:44 Possession 21:16

Scoring Plays

12 scores
Q1 8:26
Brock Purdy complete pass to Mike Evans for 2 yards, lateral to Deebo Samuel for 80 yards (Eddy Pineiro Kick)
0–7
Q2 14:55
Mike Evans 23 Yd pass from Brock Purdy (Eddy Pineiro Kick)
0–14
Q2 3:03
Chad Ryland 26 Yd Field Goal
3–14
Q2 0:23
Chad Ryland 41 Yd Field Goal
6–14
Q2 0:00
Eddy Pineiro 57 Yd Field Goal
6–17
Q3 11:07
Christian McCaffrey 1 Yd Rush (Eddy Pineiro PAT Failed)
6–23
Q3 3:02
Michael Wilson 5 Yd pass from Jacoby Brissett (Chad Ryland Kick)
13–23
Q4 13:06
Jeremiyah Love 1 Yd pass from Jacoby Brissett (Chad Ryland Kick)
20–23
Q4 8:42
George Kittle 10 Yd pass from Brock Purdy (Eddy Pineiro PAT Failed)
20–29
Q4 2:51
Jacoby Brissett 1 Yd Rush (Chad Ryland Kick)
27–29
Q4 1:31
George Kittle 20 Yd pass from Brock Purdy (Eddy Pineiro Kick)
27–36
Q4 0:34
Chad Ryland 49 Yd Field Goal
30–36

Week 3: Cardinals Visit 49ers After a Week of Opposite Directions

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The Arizona Cardinals visit the San Francisco 49ers on Sunday, September 27. Arizona is 1-1 after a 31-7 home loss to Seattle in which it gained 151 yards and Jacoby Brissett threw for 95, and cornerback Will Johnson could miss the season with a neck injury. San Francisco is 2-0 after a 35-13 win over Miami in which Brock Purdy went 20 of 22 for 287 yards; receiver De'Zhaun Stribling is out about 10 weeks and tight end Jake Tonges is done for the season. Wednesday update: San Francisco put C.J. West on injured reserve, DeMarcus Robinson is out three to six weeks, and Mike Evans is being managed through a sore hip.

Purdy's start

Twenty of 22 against Miami and three touchdowns against the Rams; the 49ers have scored 62 points.

Arizona's Week 1 was the outlier

The Cardinals beat the Chargers in Week 1's biggest upset, then managed 151 yards against Seattle.

San Francisco's receiver depth

Stribling and Pearsall are out, Christian Kirk cannot return until after Week 4; George Kittle and Christian McCaffrey are the offense.

Pregame AI Prediction

Winner called correctly Confidence: High

How the prediction did

Predicted 13-27 (Cardinals vs 49ers), final was 30-36. Right winner, but this High-confidence pick was a 6-point game instead of a 14-point one. Brock Purdy threw four touchdown passes, including an 80-yard score on a lateral to Deebo Samuel. Jacoby Brissett completed 38 of 52 passes and Arizona held the ball for nearly 39 minutes. The 49ers lost Trent Williams, Dre Greenlaw and Mike Evans to injuries.

Cardinals
13
22% to win
VS
49ers
27
78% to win
Cardinals 22% 49ers 78%

San Francisco is the most efficient offense in the league through two weeks

Purdy has 12 incompletions in two games; Arizona just allowed 381 yards to Seattle.

Arizona's offense has one good game

Twenty-six points in Los Angeles, seven at home, and now a road trip to a defense that held Miami to six through three quarters.

The Cardinals' secondary lost Johnson

Starling Thomas steps in against Kittle and McCaffrey; the projection is two scores.

The second of the week's two widest leans. Arizona's win in Los Angeles keeps the model from going higher.

Venue

Levi's Stadium
Santa Clara, CA
Attendance: 70,687

Closing Line

SF -7.5
O/U 48.5
via DraftKings

Officials

Sarah Thomas Down Judge
Brad Allen Referee
Chad Hill Side Judge
Anthony Flemming Field Judge
Walter Flowers Line Judge

Futures odds for these teams

Super Bowl futures, win totals & where to bet

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49ers Injuries

De'Zhaun Stribling
WR · Surgery
Injured Reserve
Brandon Aiyuk
WR · Not Specified
Out
Marques Sigle
S · Not Specified
Questionable
Garret Wallow
LB · Strain
Questionable
Luke Gifford
LB · Not Specified
Questionable

Cardinals Injuries

Walter Nolen III
DT · Not Specified
Questionable
Jon Gaines II
G · Not Specified
Questionable
Kendrick Bourne
WR · Fracture
Out
Bam Knight
RB · Concussion
Questionable
Jeremiyah Love
RB · Not Specified
Questionable